
OPUS17 2019/33/B/ST5/01271
Novel nanocatalysts in the continuous - flow selective hydrogenation processes towards formation of pharmaceutical intermediates
Leader: dr habil. Anna Śrębowata Professor IChF
Institute of Physical Chemistry (IChF) Polish Academy of Sciences
The main goal of OPU17 project is to create a fundamental basis for the synthesis of the novel and economical nano-catalysts for the production of fine chemicals and pharmaceutical intermediates in continuous-flow conditions. The research strategy focuses on the development of readily available 3d transition metals (Co, Cu, Fe) supported on active carbons, hydrotalcite, beta zeolites and resins, active in continuous-flow hydrogenation of the precursors of relevance to the fine and pharmaceutical industries.
Our research allows to create a relationship between the structure of the catalysts and their reactivity in these processes.
This project is a part of the current global trend in green chemistry research which is concentrated on afford simplified workup and large-scale synthesis (scalability), handling of various substrates in sequence with the same catalyst, and reduction of catalyst amount.
This project is realized in cooperation with the Laboratoire de Reactivité de Surface Université Pierre et Marie Curie in Paris and Unipetrol Centre of Research and Education in Litvínov.

Opus 17 News
LVI Annual Symposium on Catalysis:
”Catalytic activity of CuZnAl hydrotalcite derived-materials in continuous flow hydrogenation” – oral presentation
„Synthesis of pharmaceutical precursors by catalytic selective hydrogenation in a continuous flow using metal nanoparticle-based catalysts grafted onto a polymer resin” – flash oral
11th Czech-Polish Catalytic Symposium – 11th CzePoCat
„Synthesis of pharmaceutical intermediates by continuous-flow hydrogenation using Fe-based catalysts" – oral presentation
„Continuous flow hydrogenation process using bimetallic catalysts for the production of pharmaceutical intermediates” – oral presentation
LV Annual Symposium on Catalysis:
„Application of transition metals in the production of pharmaceutical intermediates using continuous flow hydrogenation”
– oral presentation
„Research of the effect of doping a copper catalyst with palladium on its catalytic properties in a chemoselective hydrogenation reaction” –flash oral
„The efficiency of hydrotalcite-derived materials in selective hydrogenation processes” – poster
4th Global Summit on Catalysis and Chemical Engineering:
„Catalytic continuous-flow hydrogenation processes for the formation of vitamin and drugs precursors” – oral presentation
15th European Congress on Catalysis (EuropaCat2023):
„Continuous - flow selective hydrogenation processes towards the formation of pharmaceutical intermediates” – oral preentation
19th Warsaw Seminar of PhD Students in Chemists – ChemSession’23:
„Chemoselctive hydrogenation of 2-methyl-2-pentenal in flow conditions with using hydrotalcite derived materials” – poster
„Wpływ domieszkowania katalizatora miedziowego palladem na jego właściwości katalityczne w reakcji selektywnego uwodornienia 2-metylopent-2-enalu” – poster
LIV Annual Symposium on Catalysis
Annual Symposium on Catalysis is an event organized by Jerzy Haber Institute of Catalysis and Surface Chemistry of the Polish Academy of Sciences. This year we had the opportunity to meet in person. Members of our team in action...
Our paricipation in 10th Czech - Polish Symposium on Catalysis (10th CzePoCat)!
The Czech - Polish Symposium on Catalysis is an event organized by VSB - Technical University of Ostrava. This year, after pandemic break, symposium was held in Ostrava. The seminar covered all the areas of catalysis with a focus on synthesis, catalysts characterization and the application in catalytic and photocatalytic processes.
Great news!
Our new article within OPUS17 „Co Loading Adjustment for the Effective Obtention of a Sedative Drug Precursor through Efficient Continuous-Flow Chemoselective Hydrogenation of 2-Methyl-2-pentenal” by Fernández-Ropero, A.J.;Zawadzki, B.; Matus, K.; Patkowski,W.; Krawczyk, M.; Lisovytskiy, D.;Raróg-Pilecka,W., Śrębowata, A. , Catalysts 2022, 12, 19. https://doi.org/10.3390/catal12010019 meet with interest of scientists.
Cover page!!!!
https://www.mdpi.com/2073-4344/12/1
Forum of the Inteligent Development, 26 - 29.09.2021 Toruń
14th of July 2021 Anna Rusiniak successfully defended her M.Sc. thesis within OPUS 17 project 2019/33/B/ST5/01271. With this defence, Anna completes her Master degree from the Cardinal Stefan Wyszyński University in Warsaw.
Congratulations Anna!!!